Familial iris melanosis--a misnomer?

[Iris mammillations. Three case reports].

CLINICAL CASES We report the cases of 3 young patients who were seen in our hospital with the diagnosis of iris mammillations. Two of them were bilateral without familial association. The third child had iris mammillations as part of an ocular melanocytosis. None of them had abnormalities in the posterior segment or the pachymetry. DISCUSSION The discovery of iris mammillations during an exam...

Iris Melanoma in Cats

Iris melanoma is a primary intraocular tumor with a high potential risc for metastasis, characterized by the presence of a single or a multiple hyperpigmentation focal areas, or diffuse hyperpigmentation of the anterior epithelium of the iris. This hyperpigmentation is due to an abnormal growth and proliferation of melanocytes. However, not any hyperpigmentation should be handled as a melanom, ...

Iris mammillations in a pair of twins with Cowden syndrome

CS: Cowden syndrome PTEN: phosphatase and tensin homolog INTRODUCTION Iris mammillation is an uncommon congenital anomaly of the eye that is rarely reported in the literature; initial reports describe iris mammillations using different terminology, such as bilateral iris melanosis, dotted Swiss iris, and bilateral diffuse iris nodular nevi. Microscopic examination finds focal nesting of spindle...

Melanosis oculi

A 20-year-old white female, who is an avid tanning-bed user, was referred for the evaluation of a pigmented lesion in her left eye. She reported occasional lid swelling, pain, tearing and light sensitivity for two years, which she attributed to wearing contact lenses. The patient received a diagnosis of ocular melanosis 6 months prior to her current presentation. On examination, the best-correc...

Case Report: Primary Leptomeningeal Melanoma in a Patient with Neurocutaneous Melanosis